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<div class="neoplasm-title-wrapper">
<div class="neoplasm-center">
<span class="neoplasm-title">
  <div class="neoplasm-hero-title">'''HemOnc.org - A Human-Curated Hematology/Oncology Reference'''</div>
'''Neoplasm.org - An open Hematology/Oncology Reference'''
</span>
</div>
</div>


Neoplasm.org is an open-access knowledge base dedicated to the rapid dissemination of oncology clinical trial results and evidence-based treatment regimens. Modeled after the collaborative spirit of the medical community, our mission is to translate complex research into actionable clinical insights—free of charge and accessible to everyone, from oncologists and researchers to students and patients.
<div class="neoplasm-center neoplasm-hero-subtitle">
HemOnc.org is the largest freely available medical wiki of [[:Category:Intervention_index|interventions]], [[:Category:Regimen_index|regimens]], and [[:Category:General_reference_pages|general information]] relevant to the fields of hematology and oncology. Any healthcare professional can [[How to contribute|sign up to contribute]]; the [[Eligibility criteria|accuracy and completeness of content]] is overseen by the [[Editorial Board]]. If this is your first time visiting, please start with the '''[[Tutorial|the tutorial page]]''', review our '''[[philosophy]]''', or just start exploring!
</div>
 
{| class="wikitable neoplasm-table neoplasm-table--stats"
|-
| colspan="4" class="neoplasm-table-title" | Content overview as of December 17, 2025
|-
! class="neoplasm-stat" | [[Tutorial#Regimens|Regimens]]: 5,652
! class="neoplasm-stat" | [[Guidelines|Guidelines]]: 1,204
! class="neoplasm-stat" | Studies: 7,228
! class="neoplasm-stat" | References: 10,377
|}


{| class="wikitable neoplasm-table"
{| class="wikitable neoplasm-table neoplasm-table--quicklinks"
|-
|-
| colspan="5" class="neoplasm-quicklinks-header" | Quick links to major topic areas
| colspan="5" class="neoplasm-table-title" | Quick links to major topic areas
|-
|-
| class="neoplasm-quicklink solid" | [[#solidtumors|Solid Tumors]]
| class="neoplasm-chip neoplasm-chip--solid"     | [[#solidtumors|Solid Tumors]]
| class="neoplasm-quicklink heme" | [[#malignantheme|Malignant Hematology]]
| class="neoplasm-chip neoplasm-chip--malignant" | [[#malignantheme|Malignant Hematology]]
| class="neoplasm-quicklink peds" | [[#peds|Pediatrics]]
| class="neoplasm-chip neoplasm-chip--peds"     | [[#peds|Pediatrics]]
| class="neoplasm-quicklink transplant" | [[#transplant|Transplant & IEC]]
| class="neoplasm-chip neoplasm-chip--tx"       | [[#transplant|Transplant & IEC]]
| class="neoplasm-quicklink classical" | [[#classicalheme|Classical Hematology]]
| class="neoplasm-chip neoplasm-chip--classical" | [[#classicalheme|Classical Hematology]]
|}
|}


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<span id="solidtumors"></span>
<span id="solidtumors"></span>


{| class="wikitable neoplasm-table"
{| class="wikitable neoplasm-table neoplasm-table--grid"
|-
! colspan="4" class="neoplasm-major neoplasm-major--solid" | '''Solid Tumors'''
|-
| colspan="4" class="neoplasm-minor neoplasm-minor--solid" | '''Breast Oncology'''
|-
| colspan="4" class="neoplasm-sub" | '''Early breast cancer (EBC)'''
|-
| class="neoplasm-cell" | [[Early breast cancer|EBC, NOS]]
| class="neoplasm-cell" | [[Early breast cancer, HR-positive|HR-positive EBC]]
| class="neoplasm-cell" | [[Early breast cancer, HER2-positive|HER2-positive EBC]]
| class="neoplasm-cell" | [[Early breast cancer, HER2-low|HER2-low EBC]]
|-
| class="neoplasm-cell" | [[Early breast cancer, HR and HER2 co-expressing|HR-positive and HER2-positive EBC]]
| class="neoplasm-cell" | [[Early breast cancer, triple negative|Early triple-negative breast cancer (eTNBC)]]
|-
| colspan="4" class="neoplasm-sub" | '''Metastatic breast cancer (MBC)'''
|-
| class="neoplasm-cell" | [[Metastatic breast cancer|MBC, NOS]]
| class="neoplasm-cell" | [[Metastatic breast cancer, HR-positive|HR-positive MBC]]
| class="neoplasm-cell" | [[Metastatic breast cancer, HER2-positive|HER2-positive MBC]]
| class="neoplasm-cell" | [[Metastatic breast cancer, HER2-low|HER2-low MBC]]
|-
| class="neoplasm-cell" | [[Metastatic breast cancer, HR and HER2 co-expressing|HR-positive and HER2-positive MBC]]
| class="neoplasm-cell" | [[Metastatic breast cancer, triple negative|Metastatic triple-negative breast cancer (mTNBC)]]
| class="neoplasm-cell" | [[Breast cancer, CNS metastases|CNS metastases]]
|-
| colspan="4" class="neoplasm-sub" | '''Breast cancer with molecular alterations'''
|-
| class="neoplasm-cell" | [[Breast cancer, BRCA-mutated|BRCA-mutated Breast cancer]]
| class="neoplasm-cell" | [[Metastatic breast cancer, PI3K pathway-altered|PI3K pathway-altered Breast cancer]]
|-
| colspan="4" class="neoplasm-minor neoplasm-minor--solid" | '''Dermatologic Oncology'''
|-
| colspan="4" class="neoplasm-sub" | '''Melanoma'''
|-
| class="neoplasm-cell" | [[Melanoma|Melanoma, NOS]]
| class="neoplasm-cell" | [[Melanoma,_BRAF-mutated|BRAF-mutated Melanoma]]
| class="neoplasm-cell" | [[Melanoma,_KIT-mutated|KIT-mutated Melanoma]]
| class="neoplasm-cell" | [[Melanoma,_NRAS-mutated|NRAS-mutated Melanoma]]
|-
| class="neoplasm-cell" | [[Uveal melanoma]]
|-
| colspan="4" class="neoplasm-sub" | '''Non-melanoma skin cancer (NMSC)'''
|-
| class="neoplasm-cell" | [[Cutaneous basal cell carcinoma|Cutaneous BCC]]
| class="neoplasm-cell" | [[Cutaneous squamous cell carcinoma|Cutaneous SCC]]
| class="neoplasm-cell" | [[Merkel cell carcinoma|Merkel cell carcinoma (MCC)]]
|-
| colspan="4" class="neoplasm-minor neoplasm-minor--solid" | '''Endocrine Oncology'''
|-
|-
| colspan="4" class="neoplasm-major-header solid" | '''Solid Tumors'''
| colspan="4" class="neoplasm-sub" | '''Other endocrine cancers'''
|-
|-
| colspan="4" class="neoplasm-subheader" | '''Soft tissue sarcoma'''
| class="neoplasm-cell" | [[Adrenocortical carcinoma]]
| class="neoplasm-cell" | [[Neuroendocrine tumor|Neuroendocrine tumor (NET)]]
| class="neoplasm-cell" | [[Neuroendocrine carcinoma|Neuroendocrine carcinoma (NEC)]]
| class="neoplasm-cell" | [[Pancreatic NET]]
|-
|-
| class="neoplasm-cell" | [[Soft tissue sarcoma|STS, NOS]]
| class="neoplasm-cell" | [[Pheochromocytoma]]
| class="neoplasm-cell" | [[Leiomyosarcoma|LMS]]
| class="neoplasm-cell" | [[Liposarcoma]]
| class="neoplasm-cell" | [[Rhabdomyosarcoma|RMS]]
|-
|-
| class="neoplasm-cell" | [[Desmoid tumor]]
| colspan="4" class="neoplasm-sub" | '''Thyroid cancer without molecular alterations'''
| class="neoplasm-cell" | [[Epithelioid sarcoma]]
|-
| class="neoplasm-cell" | [[Gastrointestinal stromal tumor|GIST]]
| class="neoplasm-cell" | [[Thyroid cancer|Thyroid cancer, NOS]]
| class="neoplasm-cell" | [[Tenosynovial giant cell tumor|TGCT]]
| class="neoplasm-cell" | [[Thyroid cancer, anaplastic|Anaplastic thyroid cancer (ATC)]]
|}
| class="neoplasm-cell" | [[Thyroid cancer, differentiated|Differentiated thyroid cancer (DTC)]]
 
| class="neoplasm-cell" | [[Thyroid cancer, medullary|Medullary thyroid cancer (MTC)]]
<span id="malignantheme"></span>
|-
 
| colspan="4" class="neoplasm-sub" | '''Thyroid cancer with molecular alterations'''
{| class="wikitable neoplasm-table"
|-
| class="neoplasm-cell" | [[Thyroid_cancer,_BRAF-mutated|BRAF-mutated Thyroid cancer]]
| class="neoplasm-cell" | [[Thyroid_cancer,_RET-positive|RET-positive Thyroid cancer]]
|-
| colspan="4" class="neoplasm-minor neoplasm-minor--solid" | '''Gastrointestinal Oncology'''
|-
| colspan="4" class="neoplasm-sub" | '''Upper GI tract'''
|-
| class="neoplasm-cell neoplasm-cell--w25" | [[Esophageal cancer|Esophageal cancer, NOS]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Esophageal adenocarcinoma]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Esophageal squamous cell carcinoma|Esophageal squamous cell carcinoma (ESCC)]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Gastric cancer|Gastric cancer, NOS]]
|-
|-
| colspan="4" class="neoplasm-major-header heme" | '''Malignant Hematology'''
| class="neoplasm-cell neoplasm-cell--w25" | [[Gastric cancer, HER2-positive|HER2-positive gastric cancer]]
|-
|-
| colspan="4" class="neoplasm-subheader heme" | '''Acute leukemias'''
| colspan="4" class="neoplasm-sub" | '''Lower GI tract'''
|-
|-
| class="neoplasm-cell heme" | [[Acute myeloid leukemia|AML]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Anal cancer]]
| class="neoplasm-cell heme" | [[Acute lymphoblastic leukemia|ALL]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Appendiceal tumor]]
| class="neoplasm-cell heme" | [[Acute promyelocytic leukemia|APL]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Colon cancer|Colon cancer, NOS]]
| class="neoplasm-cell heme" | [[CNS leukemia]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Colon cancer, RAS wild-type|RAS wild-type colon cancer]]
|}
 
<span id="peds"></span>
 
{| class="wikitable neoplasm-table"
|-
|-
| colspan="4" class="neoplasm-major-header peds" | '''Pediatric Neoplasms'''
| class="neoplasm-cell neoplasm-cell--w25" | [[Colorectal cancer|Colorectal cancer (CRC), NOS]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Colorectal cancer, BRAF-mutated|BRAF-mutated CRC]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Colorectal cancer, HER2-positive|HER2-positive CRC]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Colorectal cancer, MSI-H or dMMR|MSI-H or dMMR CRC]]
|-
|-
| colspan="4" class="neoplasm-subheader peds" | '''Pediatric solid tumors'''
| class="neoplasm-cell neoplasm-cell--w25" | [[Colorectal cancer, RAS wild-type|RAS wild-type CRC]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Rectal cancer]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Small bowel adenocarcinoma]]
|-
|-
| class="neoplasm-cell peds" | [[Neuroblastoma]]
| colspan="4" class="neoplasm-sub" | '''Hepatobiliary cancer'''
| class="neoplasm-cell peds" | [[Wilms tumor]]
| class="neoplasm-cell peds" | [[Osteosarcoma, pediatric|Osteosarcoma]]
| class="neoplasm-cell peds" | [[Ewing sarcoma, pediatric|Ewing sarcoma]]
|}
 
<span id="transplant"></span>
 
{| class="wikitable neoplasm-table"
|-
|-
| colspan="4" class="neoplasm-major-header transplant" | '''Transplant & Immune Effector Cells'''
| class="neoplasm-cell neoplasm-cell--w25" | [[Biliary tract cancer]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Cholangiocarcinoma]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Gallbladder cancer]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Hepatocellular carcinoma|Hepatocellular carcinoma (HCC)]]
|-
|-
| class="neoplasm-cell transplant" | [[Allogeneic HSCT]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Periampullary adenocarcinoma]]
| class="neoplasm-cell transplant" | [[Autologous HSCT]]
| class="neoplasm-cell transplant" | [[CAR-T]]
| class="neoplasm-cell transplant" | [[GVHD]]
|}
 
<span id="classicalheme"></span>
 
{| class="wikitable neoplasm-table"
|-
|-
| colspan="4" class="neoplasm-major-header classical" | '''Classical Hematology'''
| colspan="4" class="neoplasm-sub" | '''Pancreatic cancer'''
|-
|-
| colspan="4" class="neoplasm-subheader classical" | '''Hemostasis and thrombosis'''
| class="neoplasm-cell neoplasm-cell--w25" | [[Pancreatic cancer|Pancreatic adenocarcinoma, NOS]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Pancreatic cancer, BRCA-mutated|BRCA-mutated Pancreatic adenocarcinoma]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Pancreatic cancer, NRG1-positive|NRG1-positive Pancreatic adenocarcinoma]]
| class="neoplasm-cell neoplasm-cell--w25" | [[Pancreatic NET]]
|-
|-
| class="neoplasm-cell classical" | [[Venous thromboembolism|VTE]]
| class="neoplasm-cell classical" | [[Hemophilia A]]
| class="neoplasm-cell classical" | [[Hemophilia B]]
| class="neoplasm-cell classical" | [[von Willebrand disease|vWD]]
|}
|}


<div class="neoplasm-footer-link">
<div class="neoplasm-center neoplasm-footer-link">'''[[Special:AllPages|Browse our complete index of pages]]'''</div>
'''[[Special:AllPages|Browse our complete index of pages]]'''
 
</div>
==Additional Information==
Created as a knowledge base for hematology & oncology providers, HemOnc.org is a collaborative wiki containing details about hundreds of hematology/oncology drugs, and thousands of treatment regimens. Content is added by hematology & oncology professionals, and undergoes [[how to contribute|continuous peer review]].
 
Any information that one feels would be helpful to other oncology providers is welcome. Visit [[how to contribute]] for more details.
 
Priorities of this project include:
<section begin=goals />
*'''Creating a database of all [[Drug index | approved systemic anticancer therapy agents and supportive medications used in the field of hematology/oncology]].
*'''Creating a database of all standard-of-care systemic anticancer therapy regimens and references to primary literature.
*'''[[:Category:Example chemotherapy order sets|Sample order sets]] and examples of supportive medications used with treatment regimens
*'''Aggregating [[External links|useful links]] to existing resources by disease, such as guidelines, information about prognosis, clinical calculators, staging, and patient resources.
*'''Creating, maintaining, and disseminating a [[Ontology|formalized ontology]] of anticancer drugs and regimens.
<section end=goals />
 
Additional possibilities for this project may include:
*Creating synopses of pivotal clinical trials and regimens
*Prioritizing regimens by their efficacy and/or toxicity
*Capturing historical regimens that were standard-of-care prior to 2005
*Checklists for common clinical scenarios/diseases
*Creating checklists that can be used for patients starting therapy with particular regimens, such as laboratory & imaging (e.g. echocardiogram, PFTs) parameters to monitor and informed consent/discussion of side effects
 
The field of hematology/oncology is ever-changing, and our hope is that other people will be interested in contributing to make it an increasingly more useful resource. The rapidly evolving nature of the practice demands a more dynamic medium than existing resources can provide and would benefit from being able to be updated in real-time from virtually any computer with internet access. We believe that the familiar format of a Wiki, made popular by sites such as [https://en.wikipedia.org/wiki/Main_Page Wikipedia], will significantly help ease-of-use and navigation.
 
<br><inputbox>
type=create
width=70
placeholder=Type the name of the page you want to create
break=no
</inputbox>

Revision as of 14:09, 28 December 2025


HemOnc.org - A Human-Curated Hematology/Oncology Reference

HemOnc.org is the largest freely available medical wiki of interventions, regimens, and general information relevant to the fields of hematology and oncology. Any healthcare professional can sign up to contribute; the accuracy and completeness of content is overseen by the Editorial Board. If this is your first time visiting, please start with the the tutorial page, review our philosophy, or just start exploring!

Content overview as of December 17, 2025
Regimens: 5,652 Guidelines: 1,204 Studies: 7,228 References: 10,377
Quick links to major topic areas
Solid Tumors Malignant Hematology Pediatrics Transplant & IEC Classical Hematology

Solid Tumors
Breast Oncology
Early breast cancer (EBC)
EBC, NOS HR-positive EBC HER2-positive EBC HER2-low EBC
HR-positive and HER2-positive EBC Early triple-negative breast cancer (eTNBC)
Metastatic breast cancer (MBC)
MBC, NOS HR-positive MBC HER2-positive MBC HER2-low MBC
HR-positive and HER2-positive MBC Metastatic triple-negative breast cancer (mTNBC) CNS metastases
Breast cancer with molecular alterations
BRCA-mutated Breast cancer PI3K pathway-altered Breast cancer
Dermatologic Oncology
Melanoma
Melanoma, NOS BRAF-mutated Melanoma KIT-mutated Melanoma NRAS-mutated Melanoma
Uveal melanoma
Non-melanoma skin cancer (NMSC)
Cutaneous BCC Cutaneous SCC Merkel cell carcinoma (MCC)
Endocrine Oncology
Other endocrine cancers
Adrenocortical carcinoma Neuroendocrine tumor (NET) Neuroendocrine carcinoma (NEC) Pancreatic NET
Pheochromocytoma
Thyroid cancer without molecular alterations
Thyroid cancer, NOS Anaplastic thyroid cancer (ATC) Differentiated thyroid cancer (DTC) Medullary thyroid cancer (MTC)
Thyroid cancer with molecular alterations
BRAF-mutated Thyroid cancer RET-positive Thyroid cancer
Gastrointestinal Oncology
Upper GI tract
Esophageal cancer, NOS Esophageal adenocarcinoma Esophageal squamous cell carcinoma (ESCC) Gastric cancer, NOS
HER2-positive gastric cancer
Lower GI tract
Anal cancer Appendiceal tumor Colon cancer, NOS RAS wild-type colon cancer
Colorectal cancer (CRC), NOS BRAF-mutated CRC HER2-positive CRC MSI-H or dMMR CRC
RAS wild-type CRC Rectal cancer Small bowel adenocarcinoma
Hepatobiliary cancer
Biliary tract cancer Cholangiocarcinoma Gallbladder cancer Hepatocellular carcinoma (HCC)
Periampullary adenocarcinoma
Pancreatic cancer
Pancreatic adenocarcinoma, NOS BRCA-mutated Pancreatic adenocarcinoma NRG1-positive Pancreatic adenocarcinoma Pancreatic NET
Browse our complete index of pages

Additional Information

Created as a knowledge base for hematology & oncology providers, HemOnc.org is a collaborative wiki containing details about hundreds of hematology/oncology drugs, and thousands of treatment regimens. Content is added by hematology & oncology professionals, and undergoes continuous peer review.

Any information that one feels would be helpful to other oncology providers is welcome. Visit how to contribute for more details.

Priorities of this project include: <section begin=goals />

<section end=goals />

Additional possibilities for this project may include:

  • Creating synopses of pivotal clinical trials and regimens
  • Prioritizing regimens by their efficacy and/or toxicity
  • Capturing historical regimens that were standard-of-care prior to 2005
  • Checklists for common clinical scenarios/diseases
  • Creating checklists that can be used for patients starting therapy with particular regimens, such as laboratory & imaging (e.g. echocardiogram, PFTs) parameters to monitor and informed consent/discussion of side effects

The field of hematology/oncology is ever-changing, and our hope is that other people will be interested in contributing to make it an increasingly more useful resource. The rapidly evolving nature of the practice demands a more dynamic medium than existing resources can provide and would benefit from being able to be updated in real-time from virtually any computer with internet access. We believe that the familiar format of a Wiki, made popular by sites such as Wikipedia, will significantly help ease-of-use and navigation.


<inputbox> type=create width=70 placeholder=Type the name of the page you want to create break=no </inputbox>

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